Cul5 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comCul5 CLIA Kit for Rat(Rattus norvegicus)

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Cul5 (Gene name),

Cullin-5 (Protein name ), CUL5_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Cul5(Vacm1);

Protein name:

Cullin-5(CUL-5);

Alternative:

Vasopressin-activated calcium-mobilizing receptor 1(VACM-1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of multiple ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes formed of CUL5, Elongin BC (TCEB1 and TCEB2), RBX2 and a variable SOCS box domain-containing protein as substrate-specific recognition component. Component of the probable ECS(LRRC41) complex with the substrate recognition component LRRC41. Component of the probable ECS(SOCS1) complex with the substrate recognition component SOCS1. Component of the probable ECS(WSB1) complex with the substrate recognition subunit WSB1. Component of the probable ECS(SOCS3) complex with the substrate recognition component SOCS3. Component of the probable ECS(SPSB1) complex with the substrate recognition component SPSB1. Component of the probable ECS(SPSB2) complex with the substrate recognition component SPSB2. Component of the probable ECS(SPSB4) complex with the substrate recognition component SPSB4. Component of the probable ECS(RAB40C) complex with the substrate recognition subunit RAB40C. May also form complexes containing CUL5, Elongin BC (TCEB1 and TCEB2), RBX1 and TCEB3. May also form complexes containing CUL5, elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL. Interacts with RNF7/RBX2, LRRC41, SOCS3, SPSB1, SPSB2, SPSB4 and RAB40C. Interacts with ASB1, ASB2, ASB6, ASB7 and ASB12.

Function:

Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

780

Sequence:

50:

100:

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300:

350:

400:

450:

500:

550:

600:

650:

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750:

780:

KMIKEQIEWL | IEHKYIRRDE | ADINTFIYMA |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000062182

Pfam:

PF00888

UniGene:

Rn.163001

String:

Q9JJ31

KEGG:

rno:64624

Uniprot:

Q9JJ31

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ELISA Kit for Rat CUL-5

Cat.:

E15273h

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96T

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ELISA Kit for Rat CUL-5

Cat.:

E15273m

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Packing:

96T

ELISA Kit for Rat CUL-5

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ELISA Kit for Rat CUL-5

Cat.:

E15273r

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96T

CLIA Kit for Rat CUL-5

Cat.:

U15273h

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Packing:

96T

CLIA Kit for Rat CUL-5

Cat.:

U15273r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat CUL-5

Cat.:

U15273m

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MSDS:

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Packing:

96T

CLIA Kit for Rat CUL-5

MSDS:

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Polyclonal Antibody for Rat CUL-5

Cat.:

P15273Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat CUL-5

Cat.:

P15273Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat CUL-5

Cat.:

P15273Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat CUL-5

Protein for Rat CUL-5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Expression of the genes encoding the vasopressin-activated calcium-mobilizing receptor and the dual angiotensin II/Vasopressin receptor in the rat central nervous system."
Hurbin A. , Orcel H. , Ferraz C. , Moos F.C. , Rabie A.
J. Neuroendocrinol.12:677-684(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Wistar.
tissue: Liver.
2.

Bienvenut W.V. , von Kriegsheim A.F. , Kolch W.
Submitted (2006-08) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-10; 80-91; 357-364; 375-384; 482-492; 502-511; 519-529; 614-620; 633-642 AND 646-658;CLEAVAGE OF INITIATOR METHIONINE;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Pheochromocytoma.

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